![]() ![]() 7 While nondrug interventions are generally presumed safe, few trials have reported information on their harms or other unintended consequences. ![]() Although drug and nondrug interventions are available to treat symptoms, support function, and improve quality of life, nondrug interventions are recommended as first line treatments for behavioral and psychological symptoms (BPSD) over antipsychotics and other medications. 5 Agitation, aggression, and other behavioral disturbances are common, 6 especially late in the disease course.ĭementia has no known cure. 4 Dementia lowers an individual's quality of life, burdens caregivers, increases institutionalization, and is costly to families and society. 3 Alzheimer's disease is the most common form of progressive dementia and-grouped with Lewy body, frontotemporal, vascular, and mixed forms-is commonly referred to as AD/ADRD (i.e., Alzheimer's disease (AD) and Alzheimer's disease related dementias (ADRD)). 1, 2 It is characterized by an acquired cognitive deficit that interferes with independence in daily activities. ![]() The goal is to understand the evidence base for effective care interventions, and to assess the potential for broad dissemination and implementation of that evidence.ĭementia is a clinical syndrome that affects about 10 percent of older U.S. The National Institute on Aging (NIA) has commissioned such a summary from the Evidence-based Practice Center Program at the Agency for Healthcare Research and Quality (AHRQ) in collaboration with the National Academies of Science, Engineering, and Medicine (NASEM). Rising rates of dementia in the United States underscore the urgent need for a summary of the available evidence for care interventions for people with dementia (PWD) and their formal and informal caregivers. Background and Objectives for the Systematic Review ![]()
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